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Mutation benefits drug effect

A new study shows that a mutation present in some cases of acute leukemia makes the disease more susceptible to high doses of a particular anticancer drug.

Inherited melanoma risk

When people know the results of genetic tests confirming they have inherited an increased risk of developing melanoma, they follow skin cancer screening recommendations more proactively.

Gene variant health risk

Nutrition researchers have identified five common genetic variations that increase the risk of metabolic syndrome, a group of factors linked to heart disease and diabetes.

Extract-N-Amp optimisation

Sigma-Aldrich is developing optimised protocols enabling Extract-N-Amp kits to join a growing range of Plug'n'Prep methods for Eppendorf AG's epMotion.

Blocking malaria transmission

By disrupting the potassium channel of the malaria parasite, a team of researchers has been able to prevent the malaria parasites from forming in mosquitoes.

Stem cells and cancer

If a crucial gene called Apc is lost or damaged, its normal function of controlling the adult stem cell population breaks down.

Fingerprint of Evolution

One of the steps in turning genetic information into proteins leaves genetic fingerprints, even on regions of the DNA that are not involved in coding for the final protein.

Looping genes

Researchers have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease.

Controlling genes

Researchers have discovered a gene in flies whose activity rises and falls depending upon the amount of protein and sugar in the insects' diets.

Turning cells into fat

Researchers report the discovery of a critical early player, so-called 3T3-L1 cells, in the path that turns cells to fat.

Continental markers

An international team of researchers has developed a technique to detect the ancestry of disease genes in hybrid, or mixed, human populations.

Transcriptional profiling of prion infection

Prion infection results in progressive neurodegeneration of the central nervous system invariably resulting in death.

Knockdown of the bovine prion gene PRNP

The authors of this study hypothesise that bovine animals with reduced PrP would be tolerant to BSE.

ALS toxic assault

Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis.

Genes impact blood pressure

Researchers have discovered that rare genetic variants can be associated with a lower risk of developing high blood pressure.

Genetics of height

Scientists are beginning to develop a clearer picture of what makes some people stand head and shoulders above the rest.

Plant hormone production

Researchers have pinpointed a small group of genes responsible for "telling" plants when, where and how to produce a hormone that is key to their development.

Treating muscle disease

sIBM is a muscle disease that affects predominantly older men, causing muscles to gradually weaken and waste away.

Virulence gene superfamily

A research team has identified an enormous superfamily of pathogen genes involved in the infection of plants.

Mitosis gets harder

A biological process taught to every pupil studying GCSE science has just become a little more complicated thanks to a new discovery.

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