An ‘in silico’ (computer simulated) model of the human body that will enable simulation of the effects of drugs and treatments on the human body is being developed by theUniversity of Sheffield-based Insigneo Institute. For more click HERE.
A study spearheaded by Scientific Director Giulio Superti-Furga at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences shows that fast-growing cancer cells are sensitive towards imbalances in the metabolism of nucleotides, the building blocks of DNA.
This vulnerability can be exploited for a radically novel antitumour therapeutic approach. Not only did the researchers from Vienna, in a joint effort with colleagues from Oxford and Stockholm, identify the enzyme MTH1 as an Achilles heel of malignant tumour cells, but also, in a wonderful twist of fate, they discovered the chemical mirror image of an existing anti-cancer drug called crizotinib to be an efficient inhibitor of MTH1 activity. For more click HERE.
Scientists at Trinity College Dublin have made a major breakthrough with important implications for sufferers of the eye disease Age-Related Macular Degeneration (AMD), which can cause central blindness in sufferers.
The scientists found that a component of the immune system, ‘IL-18’, acts as a guardian of eyesight by suppressing the production of damaging blood vessels behind the retina at the back of the eye. For more click HERE
Antibiotics are used in apiculture to treat bacterial diseases, such as foulbrood. Antimicrobial drugs are effective against their diseases; however, antibiotic drug residues in honey pose a risk to human health. Randox Food Diagnostics offers excellent tools for on-site screening of antimicrobials in honey.
For more click HERE.
Asynt has developed a new adaption of its Vortex overhead stirrer, called the Vortex Blend, specifically to cater for the requirement of scientists who need to test new formulations and blends in parallel. For more click HERE.
Interscience's BagMixer S and BagMixer SW are new silent lab blenders for improved lab work comfort to answer demands for safe microbiological analyses. For more, click HERE.
With a capacity of 728 litres, Panasonic's Eco VIP KM-DU73Y1E -86°C upright freezer is claimed to be the most energy-efficient of its size and is suitable for sample storage within hospitals, biomedical research institutes and biopharmaceutical laboratories.
Energy savings lead to reduced running costs as well as environmental benefits, and so the KM-DU73Y1E provides a range of advantages to all users of ultra-low temperature freezers
For more click HERE
Speedy Breedy is a portable,instrument that finds contamination in water days faster than sending samples to a lab. It can find contamination in a whole range of applications that include food, beverages, beer, paint, oil, functional fluids, stem cells, donor organs, starch, ballast water and pig semen. For more click HERE.
In one of the first studies to show a significant association between Bisphenol A (BPA) and cancer development, University of Michigan School of Public Health researchers have found liver tumours in mice exposed to the chemical via their mothers during gestation and nursing.
"We found that 27 per cent of the mice exposed to one of three different doses of BPA through their mother's diet developed liver tumours and some precancerous lesions. The higher the dosage, the more likely they were to present with tumours," said Caren Weinhouse, U-M doctoral student in the School of Public Health's Department of Environmental Health Sciences and first author of the paper published online in Environmental Health Perspectives.
For more click HERE
The circadian clock is a molecular network that generates daily rhythms, and is present in both plants and animals.
A University of Leicester research team led by Dr Eran Tauber has studied genetic variation in circadian clock genes in wild populations of the fruit fly, Drosophila melanogaster – and has discovered that their genes have developed different genetic variations that are functionally important.
Here, Professor Bambos Kyriacou at the Department of Genetics at the University of Leicester talks about fruit flies, and circadian rhythms.
For more click HERE.