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Preclinical imaging systems for advanced translational research

9th September 2016

Posted By Paul Boughton


Bruker has unveiled two new preclinical imaging systems designed to deliver highest performance and improved convenience for routine imaging, and enable novel translational research into the causes, progression, as well as potential diagnosis and treatment of disease.

Bruker’s new SkyScan 1276 microCT (X-ray micro-Computed Tomography) combines highest resolution, speed, accessibility and other innovations to advance improved in vivo scanning of small laboratory animals and of in vitro biological samples in preclinical studies.

With continuously variable magnification, including a smallest pixel size of 2.8µm, and a shortest scanning cycle of 3.9 seconds, the SkyScan 1276 gives researchers access to highest-quality images at higher throughput. The SkyScan 1276 also is the world’s first in vivo microCT system with rapid helical scanning, and with InstaRecon technology to reconstruct images up to 8000x8000 pixels per slice, faster than any other conventional algorithm. Researchers will also benefit from easy system control by a user-friendly touchscreen and the ability to view and share images on any iOS or android mobile device.

Bruker’s Silicon photomultiplier (SiPM) PET insert for simultaneous PET/MRI (Positron Emission Tomography/Magnetic Resonance Imaging) investigations in mice and rats. This novel PET insert is compatible with MRI systems up to 15.2 Tesla and allows simultaneous measurements for the perfect correlation of PET and MRI data in space and time, in order to examine tracer kinetics, therapeutic agent distribution and animal physiology. The new, work-in-progress PET insert has been successfully installed in a 7 Tesla 30cm magnet in a Bruker preclinical MRI system at the University of Leuven, Belgium under the guidance of Dr Christophe Deroose, Professor of Nuclear Medicine. 





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