Reproducible low temperature reactions on small-to-medium scale

The Asynt DrySyn SnowStorm offers a solution to laboratories undertaking low temperature reaction chemistries.

Available in a choice of configurations, the DrySyn SnowStorm system provides controlled cooling and heating for sub-ambient parallel chemistry without the need for jacketed reaction vessels, or ice baths. Operating with a suitable chiller / circulator, a DrySyn SnowStorm system provides accurate, stable temperature control down to -50°C and up to 150°C.

Dr Geraint Jones, Associate Director of Chemistry at Sygnature Discovery, commented: "Being able to maintain a sub-ambient temperature sometimes for significant periods is really important for reaction reproducibility. The DrySyn SnowStorm connects to an external chiller unit and holds temperatures at a set-point for as long as is required. Setting temperature ramping profiles is also possible which is important in optimisation studies and is a real added benefit to us"

His colleague Mark Mills, Senior Research Chemist at Sygnature Discovery added, "We purchased the DrySyn SnowStorm to achieve tight temperature control (at -20°C) for a reaction involving a stereoselective cyclisation. If we had not been able to maintain this temperature for a sustained period, racemisation could have occurred. We selected this Asynt equipment because it integrated well into our way of working and allowed the use of round-bottomed flasks in a variety of sizes, thereby providing the flexibility to conduct small to medium scale reactions".

For more information, visit: www.sygnaturediscovery.com or www.asynt.com

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