96-well exposure of air-liquid interface (ALI) cell cultures on HTS plates: introducing a new solution.
The Vitrocell 96 continuous flow exposure system represents a breakthrough in high-throughput research involving human cell cultures or tissues exposed directly to airborne substances such as gases, complex mixtures and particles, including nanoparticles. This innovative system faithfully replicates the conditions of human physiological exposure at the air-liquid interface (ALI). With the capacity to perform up to 11 dilutions, each with 8 replicates, and dedicating the 12th insert row for clean air control with also 8 replicates, the 96-well plates offer exceptional versatility, allowing for the assessment of multiple endpoints in a single experiment.
The new system provides a comprehensive 96-well turnkey solution that includes all necessary flow controllers and an integrated humidification station. To ensure the optimal preservation of aerosol compounds and precise control of humidity levels, the Vitrocell 96 incorporates a climatic chamber maintained at 37°C.
Wide Range of Options
Researchers benefit from a diverse selection of gas mixture and aerosol generators, spanning from volatile organic compound (VOC) generators to smoking/vaping robots as well as liquid and dry powder generators. This versatility empowers scientists to tailor their experiments to the specific needs of their research projects.
Quality Assurance and Global Support
Prior to delivery, the Vitrocell 96 undergoes rigorous testing to meet agreed factory acceptance test (FAT) criteria, ensuring its reliability and accuracy. Installation and training services are provided worldwide by experienced Vitrocell engineers, guaranteeing a smooth and successful implementation of the system. Post-installation, the company’s commitment to customer satisfaction continues through its V-Care service package, ensuring that researchers receive the support they need to maintain or speed up the pace of their science.