AMS Bio has launched Extragel, a like-for-like replacement for Matrigel, Geltrex and Cultrex Basement Membrane Extract (BME).
Extragel is a reconstituted matrix hydrogel formed by basement membrane components extracted from mouse tumour tissues which are rich in extracellular matrix proteins. Designed to be used undiluted or diluted to a specific protein concentration, Extragel is proven to be a highly effective growth scaffold for in vivo xenograft generation, pluripotent stem cell maintenance/differentiation, angiogenesis and advanced 3D culture applications. Extragel is composed of laminin, collagen IV, and heparan sulfate proteoglycans plus various growth factors including epidermal growth factor, platelet-derived growth factor, nerve growth factor, basic fibroblast growth factor (FGF-2), transforming growth factor-β, and insulin-like growth factor.
Formulated to be free of LDEV as well as mycotoxins including fungi, bacteria, and mycoplasma, researchers using Extragel matrix can generate optimised gels in under 30 minutes at 37°C. AMS Bio implements strict quality inspection to ensure excellent product stability and high batch-to-batch consistency.