Improving consistency and recoveries

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A new range of BioVyonTM C18 silica columns and microplates has been introduced by Porvair Filtration Group for use in low volume Solid Phase Extraction (SPE) assays.

Traditional packed bed SPE columns and microplates perform relatively inefficiently when using the shallow sorbent beds necessary to get good recovery from smaller sample volumes. By immobilising the C18 sorbent within the porous BioVyon polymer - Porvair have created a novel, high surface area matrix that provides unmatched control of flow rate. Further the immobilised C18 sorbent cannot form liquid channels and does not require inert frits to support it thereby minimising hold-up volume. The combination of these attributes has enabled Porvair to introduce a new range of SPE columns and microplates that provide higher consistency and greater recoveries for small sample volume assays.

BioVyon C18 is initially being offered in 96-well microplates as a 10mg per well loading suitable for low volume bioassay preparation and clean-ups. In the popular 1ml cartridge format, BioVyon C18 is available in a choice of 12.5, 25 and 50mg loadings to suit your application.

BioVyonTM is made from a pharmaceutical grade polyethylene material. The manufacturing process is proprietary to the Porvair Filtration Group. Using novel ActiVyonTM technologies, Porvair Filtration Group is pioneering chemical modification and activation of BioVyon to create a family of new materials that represent new opportunities for the simple, robust and ultra fast purification of biological materials and molecules. Currently the BioVyon family includes columns and microplates for high performance solid phase extraction (SPE) and antibody purification.

The Porvair Filtration Group is an acknowledged world leader in the development and manufacture of specialist porous materials and filtration systems. With expertise in a wide range of media, and over 150 years of accumulated experience in filtration, the Group designs and manufactures high performance filtration, separation and purification products and systems for the most demanding applications and environments.

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