The use of evaporative light scattering detection (ELSD) within in the field of HPLC is continuously growing, due to its universal nature.

For the development and commercialisation of its proprietary gene transport unit (GTU) technology and GTU product applications in DNA vaccination and immune therapy, Finnish company FIT Biotech has won Frost & Sullivan's 2004 European Excellence in Technology Award.

The perceived utility of biosensors ­ analytical devices based on molecules that recognise specific biological substances ­ within the consumer health, biotechnology and biomedical industries is well established.

The functional genomics revolution started when studies of worms and flies showed the possibility of neutralising the expression of a specific gene by a previously unknown mechanism, called RNA interference or RNAi.

Much has been written about the use of wipes in the electronics industry, but little or nothing about the requirements for wipes within life science cleanrooms. The assumption has also been made that life science requirements are very similar.

With the eight actively driven rollers of the planetary driven IPC and IPC-N tubing pump series, a peristaltic delivery with minimal pulsation is possible and high precision is guaranteed.

Normally a combined pH glass electrode is only stored in c(KCl)=3mol/L because it is then immediately ready for use without prior conditioning of the diaphragm.

The reduced efficacy of existing drugs and a lack of treatments for many new diseases are expected to drive expansion in the biopharmaceuticals market.

As the properties of a polymer can depend greatly on its size, there has always been a need to be able to measure it, both in terms of molar mass and physical size. The earliest polymers studied were materials such as elastomers and, later, synthetic polymers like polyethylenes or polypropylenes. The range of samples studied has since increased enormously with the realisation that many biological functions are also controlled by molar mass, size and shape.

Laboratories ­ mostly R&D laboratories ­ accumulate vast amounts of data utilising electronic laboratory notebooks (ELNs). ELN users need ways to be able to better analyse that data, identify correlations and draw better conclusions. In real life, the flood of data often overstretches users. Most ELNs lack adequate search facilities and simple full text search capabilities, such as those ofassemble useful information from the data an Internet search engine, are not enough to assemble useful information from the data.

Eric Trompier outlines how to achieve state-of-the-art pH-stat titration.

Darlene Wood reports on the use of charged-coupled device imaging systems in life science research imaging applications.

Since its formation in 1988, The Automation Partnership (TAP) has pioneered the development and implementation of industrial automation solutions to the world's leading pharmaceutical, agrochemical, biotechnology and genomics companies.

Since early 2003, Broadley-James has quietly been signing deals with key players in the life science industry to supply its BioNet Bioreactor Control System. This, says the company, is the first digitally networked bench-top bioreactor for cell culture and microbial applications. It has just been announced that Emerson Process Management is playing a key role in this as the BioNet system uses Emerson PlantWeb digital plant architecture and solutions.

VARIO diaphragm pumps offer the most advanced combination of high performance mechanics and materials with the latest in electronic control technology.

What does the Danish chemist Johan Kjeldahl have to do with boats? Initially nothing, and yet a boat plays a decisive role in the analytical method he developed for the determination of nitrogen.

Eric Trompier describes the most important factors to be taken into account in order to ensure reliable potentiometric titration measurements and looks at how modern instruments help laboratories achieve them effortlessly.

When undertaking particle size measurements it is important to validate the analysis method to ascertain both its robustness and integrity. Steve Ward-Smith and Alan Rawle review the steps that should be taken when validating laser diffraction methods for particle size analysis.

A major factor driving the decision on which circulator will best control the temperature of a process within a chemical reactor is the cooling power at the process temperature.

Measuring powder flowability can be a major problem,particularly for the pharmaceutical industry. Here Reg Freeman describes new powder rheometer technology that helps theearly stage assessment of powder property and therefore theability to design formulations with the required characteristics.