Recombinant technology specialist Sino Biological has launched the XPressMAX Cell-Free Protein Synthesis Kit (Cat#: CFKIT02). The solution is designed to supercharge AI-driven high-throughput screening pipelines for antibody drug discovery.
XPressMAX cell-free protein synthesis kit
The kit leverages advanced cell-free protein synthesis technology to enable rapid, efficient in vitro production of target proteins and antibodies – eliminating the constraints of traditional cell-based expression systems. By integrating with AI-powered screening platforms, XPressMAX enables researchers to accelerate the identification and optimisation of promising antibody candidates, reducing both development timelines and costs.
“AI is revolutionising antibody screening, but it demands expression systems that can match its speed and throughput,” said Dr. Jie Zhang, Sino Biological’s general manager. “XPressMAX achieves rapid, high-success expression of challenging proteins in as little as three hours.”
Based on an E. coli lysate and fully supplemented with essential transcription and translation components, the kit enables direct protein synthesis from plasmid or PCR templates. Specifically designed for antibody drug discovery, XPressMAX enables rapid expression and validation of VHH, scFv, Fab, and Miniprotein. Leveraging XPressMAX, Sino Biological has established a high-throughput cell-free expression platform that validates 2,000+ scFv/VHH molecules in three to four weeks to match AI’s rapid iteration.
XPressMAX highlights
- Ultra-fast synthesis: Synthesis completed in three hours
- High success rate: over 99%, reliable system performance
- Supports complex disulfide bonding: Native folding and bioactivity without additional enhancers
“Our XPressMAX is a significant advancement in research tools and reagents for next-generation therapeutic discovery,” said Dr Rob Burgess, chief business officer at Sino Biological US, Inc. “By combining rapid, reliable protein expression with intelligent screening, we are helping our partners compress antibody discovery timelines without compromising quality.”
Researchers can visit the Sino Biological website to explore more about XPressMAX or click here to request a free sample.
