Stunner delivers low-volume ADC characterisation on up to 96 samples at a time
Unchained Labs has launched a new application on Stunner that is capable of delivering rapid, low-volume antibody-drug conjugate (ADC) characterisation on up to 96 samples at a time.
ADCs are complicated, making pinning down what has been made a difficult task, especially in early development when sample details are scarce, and the process is still in flux. Simple UV/Vis methods are unable to resolve overlapping signals without perfect inputs, while heavy-duty analytical tools risk burning through the sample and killing the throughput with tedious method development.
Stunner facilitates fast, reliable answers on drug-antibody ratio (DAR), concentration, and size, even when sampling information is limited. It can cleanly separate antibody and drug contributions, unraveling the overlapping signals that confuse standard UV/Vis methods. By combining UV/Vis and dynamic light scattering, Stunner enables researchers to go through conjugate comparisons at an accelerated pace, check consistency across process steps, and make better informed decisions at earlier stages in development.
Krystin Schmidt, VP of marketing at Unchained Labs, said, “ADCs are exploding, and researchers need a fast way to screen conjugates before investing in deeper characterisation. Stunner’s new ADC Decode application serves up the simplest, most walk-up way to get DAR and concentration analysis.”
