The technology enables live reaction monitoring and non-destructive analysis
Horiba, Japanese manufacturer of precision instruments, has launched the PoliSpectra rapid Raman plate reader (RPR) for raman high-throughput screening.
“RPR was designed to support time-sensitive applications in drug discovery and formulation development and to address challenges faced during pharmaceutical drug development,” said Horiba Raman plate reader product manager Dr Aashish Tuladhar.
“Our RPR technology provides a unique combination of sensitivity, speed and automation integration, empowering researchers to monitor reactions in real time and optimise processes more efficiently.”
The PoliSpectra RPR enables live reaction monitoring, with 96 liquid wells measured by Raman spectroscopy in one minute. While monitoring, the PoliSpectra RPR generates immediate reaction trending information.
Non-destructive analysis through rapid Raman reading technology supports live process monitoring through rapid plate reading and transfer at reaction temperature. A plate heater also assists with maintaining reaction temperature.
During a well plate transfer, a robotic handling tool repositions the plate back into the liquid handler to continue reactions, eliminating the cool-down time and providing a quicker, streamlined alternative to traditional methods.
The PoliSpectra RPR offers full automation. A motorised door, dedicated software and server access allow for easy integration with automated liquid handling systems or robotic arm microplate loaders.
Control software of the PoliSpectra RPR features OPC-UA or REST API interfaces for automated integration with standard pharmaceutical systems, supporting efficient monitoring of bioprocesses and drug discovery.
