To help with drug discoveryhttps://www.creative-biolabs.com/
Global leader in biotechnology services, Creative Biolabs, has launched integrated membrane protein product suite, designed to help researchers overcome traditional bottlenecks in membrane protein research.
Membrane proteins continue to be among the most intractable targets in biotechnology. These proteins (G protein-coupled receptors, ion channels, transporters) comprise more than 50% of all drug targets and play central roles in cellular communication, signaling and disease development. Their structural heterogeneity and instability have been long-standing obstacles for research.
“Membrane proteins are major drug targets and more than 50% of all FDA-approved drugs target membrane proteins, but they are difficult to express and stabilise,” said a senior scientist at Creative Biolabs. “Our products allow researchers to use well-behaved, reproducible, high-quality products that preserve native protein structure for more physiologically relevant functional studies and drug screening.”
Over the past few years, Creative Biolabs has built the MemDX membrane protein platform and a comprehensive catalog of membrane protein products to aid antibody and therapeutic development. Their products range from GPCR protein products, transporter protein products, CAR-T therapy target protein products and biomarkers and CD protein products.
Other highlights include:
* Membrane Protein Stable Cell Line Products
Stable cell lines offer consistent expression of GPCRs, ion channels, immune checkpoints, and oncology-related targets, serving as robust models for drug discovery and validation.
* Membrane protein expression kits
Creative Biolabs has developed a series of cell-free expression systems for high-quality, large/medium-scale membrane protein expression.
* Membrane protein solubilisation and stabilisation reagents
These products preserve native protein conformations, a critical step for downstream assays and therapeutic development. They provide comprehensive products to advance research, including detergent, phospholipid, nanodisc, and polymer.
The dedication of Creative Biolabs to furthering biotechnology research is shown in these integrated solutions. The company helps scientists decrease experimental risk, expedite timeframes, and provide repeatable results by fusing innovation and dependability.
“Creative Biolabs has truly changed the way we approach membrane protein research,” said one oncology drug development researcher. “its high-quality, ready-to-use products are able to help us tackle complex membrane protein challenges with confidence and speed.”
