The module offers fluorescence sensitivity for dim and complex multicolour experiments.
Beckman Coulter Life Sciences has launched the modular CytoFlex mosaic spectral detection module.
The module offers fluorescence sensitivity for dim and complex multicolour experiments and can detect nanoparticles as small as 80nm.
“As a central feature of the CytoFlex platform, this innovation is focused on pairing ease-of-use with powerful, sensitive acquisition technology to remove the intimidation encountered in many flow cytometry instruments,” said Beckman Coulter product manager Matthew Goff.
“Investigators can now easily switch between their true conventional detection system and this advanced spectral detection system, while maintaining a familiar sample management and user experience, all without having to invest in a separate instrument.”
It provides two unmixing algorithms and up to 10 autofluorescence channels, with up to 88 detection channels.
The CytoFlex module is powered by an algorithm which improves resolution along with unmixing accuracy checks to ensure efficiency.
Spectral analysis can provide richer, nuanced data about immune cell subsets and their functions and interactions.
Unlike conventional flow cytometry which only measures the peak of emission, spectral flow cytometry acquires the full emission spectrum of each antibody-associated fluorophore across all lasers.
Such an analysis delivers a more detailed and precise characterisation of cellular properties, advancing understanding of complex biological systems and diseases within each sample.
The module comes with tools to streamline full spectral workflow and reduce the need for extensive training. Access to the FluoroFinder panel builder and Cytobank Premium assist with this as well.
