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How common virus eludes detection

Viruses have numerous tricks for dodging the immune system. A study details one of these stratagems, identifying a protein that enables cytomegalovirus to shut down an antiviral defence.



Imaging: Cell infected by virus viewed

A recently published article describes the researchers' findings about the life cycle of the Sulfolobus turreted icosahedral virus.



Biotechnology: Flu virus protein damages lung cells

A protein in influenza virus that helps it multiply also damages lung epithelial cells, causing fluid buildup in the lungs, according to new research.



Influenza virus in 1918 and today

Scientists argue that we have lived in an influenza pandemic era since 1918, and they describe how the novel 2009 H1N1 virus is yet another manifestation of this enduring viral family.



Cancer drug linked to brain virus

Rituximab is the most important and widely used cancer drug for lymphoma. It is also approved for treatment of rheumatoid arthritis and is widely used off-label to treat multiple sclerosis, lupus erythematosus and autoimmune anemias.



Visualizing virus replication in 3D

Scientists at the Hygiene Institute at Heidelberg University Hospital were the first to present a three-dimensional model of the location in the human cell where the virus is reproduced.



Cancer-causing virus associated HIV

Infection with anal human papillomavirus, a virus that can cause anal and cervical cancers, is associated with a higher risk of new HIV infection in previously HIV-negative men who have sex with men.



The structure of a giant virus

Scientists have determined the basic design of the mimivirus's outer shell, or capsid, and also of the hundreds of smaller units - called capsomeres - making up this outer shell.



Minimising the spread of deadly Hendra virus

Groundbreaking CSIRO research into how the deadly Hendra virus spreads promises to save the lives of both horses and humans in the future.



Pathological Clues to How the SARS Virus Kills

Severe acute respiratory syndrome (SARS) first emerged in Guangdong Province, China, in November 2002.



Tumour-killing virus

New findings show that a specialised virus with the ability to reproduce its tumour-killing genes can selectively target tumours in the brains of mice and eliminate them.



GMP-compliant methodology produces live virus vaccines

While several methods are known for producing live virus preparations for vaccines, the manufacture of infectious virus preparations of consistently good purity and yield has proved difficult.



Novel virus entry mechanism discovered

Scientists working with Vaccinia virus, the smallpox vaccine, have discovered a novel mechanism that allows poxviruses to enter cells and cause infection.



WHO updates guidelines for labs dealing with influenza A virus

As avian flu spreads, the World Health Organisation has issued new guidelines for identifying avian influenza A virus in specimens from humans. Sean Ottewell reports.



Manipulating the Schmallenberg virus genome to understand how it causes disease

Scottish researchers have developed methods to synthesize and change the genome of a recently discovered virus, in a bid to understand how it induces disease among livestock such as cattle, sheep and goats.



Catching the common cold virus

Researchers on the virus behind nearly half of all cold infections explains how and where evolution occurs in the rhinovirus genome and what this means for possible vaccines.



Epstein-Barr virus linked to MS

Epstein-Barr virus, the pathogen that causes mononucleosis, appears to play a role in the neurodegeneration that occurs in persons with multiple sclerosis, according to researchers.



Flu virus foiled again

Researchers have identified a common Achilles' heel in a wide range of seasonal and pandemic influenza A viruses.



Development of a model for marburg virus

The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever.



Vaccine for Ebola virus

An international team of researchers has successfully tested several Ebola vaccines in primates and are now looking to adapt them for human use, opening the door to a cure of a deadly disease.



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