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Viral contaminations in lab and manufacturing facilities

Dr Marcin Los outlines how to tackle the reoccurring problems of viral contaminations



Viral protein structure study offers HIV hope

The UK's National Physical Laboratory is involved in a collaborative project that is helping to further the understanding of HIV viral protein structure which could lead to new molecular medicines.



Viral Life Cycle of Malignant Catarrhal Fever

The mysterious life cycle of a sheep virus that causes malignant catarrhal fever has been discovered by scientists and their university collaborators-the first step in developing a vaccine against the disease.



Key to early stages of viral infection

Scientists have identified a molecule that defines which cells are destined to become memory T cells just a few days after a viral infection begins.



Vaporised viral vector shows promising pharmacology advance

A new lung cancer therapy employing a vaporised viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials, according to researchers.



How brain responds to viral infection

Scientists have discovered that astrocytes respond to a molecule that mimics a viral infection using cellular machinery similar to that used by classical immune cells in the blood.



Researchers pioneer treatment for viral infection common in children

Researchers at Imperial College London have discovered a new way in which a very common childhood disease could be treated. In the first year of life, 65 per cent of babies get infected by Respiratory Syncytial Virus (RSV). This causes bronchiolitis, and is thought to kill nearly 200,000 children every year worldwide.



Protein production: going viral

A research team of scientists from EMBL Grenoble and the IGBMC in Strasbourg, France, have, for the first time, described in molecular detail the architecture of the central scaffold of TFIID: the human protein complex essential for transcription from DNA to mRNA.



"Junk DNA" can sense viral infection

Once considered unimportant "junk DNA," scientists have learned that non-coding RNA (ncRNA) - RNA molecules that do not translate into proteins - play a crucial role in cellular function. Mutations in ncRNA are associated with a number of conditions, such as cancer, autism, and Alzheimer's disease.



Hepatitis C viral replication requirement

Researchers report finding nearly 100 genes that support the replication of HCV and show that blocking several of them can suppress viral replication in cultured cells.



Key molecules inhibit viral production

Researchers found that peptides derived from the core protein of hepatitis C. inhibit not only dimerisation of the core protein, but also production of the actual virus itself.



Viral genome sequencing

Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, SARS, Ebola, and Dengue.



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