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Ebola virus vaccines

New study highlights effectiveness of a herpesvirus cytomegalovirus-based vaccine against Ebola virus



Equitable access to influenza vaccines not in sight

A recent article provides a case study of the negotiations to increase access to vaccines for influenza strains that suggest the goal of equitable access is far from certain.



HPV vaccines may reduce a wide range of genital diseases

High-coverage human papillomavirus vaccinations among adolescents and young women may result in a rapid reduction of genital warts, cervical cell abnormalities, and diagnostic and therapeutic procedures, researchers report.



Trials of 2009 H1N1 influenza vaccines in healthy adults

The early data from clinical trials indicate that 2009 H1N1 influenza vaccines are well tolerated and induce a strong immune response in most healthy adults when administered in a single unadjuvanted 15-microgram dose.



Pharmacology: Effective cancer vaccines

Researchers announced promising data from a clinical study showing patient-specific cancer vaccines derived from patients' own cancer cells and immune cells were well tolerated and resulted in impressive long-term survival rates.



Analysis could lead to better vaccines

Recent research points to the critical importance of what has been a poorly appreciated aspect of the interaction between a virus and those naturally produced defensive proteins called antibodies that fight infection.



Vaccines may need reworking

Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection.



New tumour vaccines

Researchers have uncovered a new way to develop more effective tumour vaccines by turning off the suppression function of regulatory T cells.



Nanoemulsion vaccines

A novel technique for vaccinating against a variety of infectious diseases - using an oil-based emulsion placed in the nose, rather than needles - has proved able to produce a strong immune response.



GMP-compliant methodology produces live virus vaccines

While several methods are known for producing live virus preparations for vaccines, the manufacture of infectious virus preparations of consistently good purity and yield has proved difficult.



Genetically modified plants to grow vaccines against killer diseases

Genetically modified plants are to be used to grow vaccines for use in the worldwide fight against HIV, tuberculosis, diabetes and rabies thanks to a grant of E12 million from the EU's Sixth Framework Programme.



Prokarium receives grant to develop next generation vaccines

A consortium comprising vaccine developer Prokarium Ltd and the University of Birmingham’s Institute of Microbiology and Infection has received an award for 'advancing the industrial application of synthetic biology'.



Access to vaccines

Building local clinical research and vaccine production capacity in developing countries will increase the global availability of affordable vaccines.



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