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Supplements induce stem cell genetic abnormalities

High doses of antioxidant nutritional supplements, such as vitamins C and E, can increase genetic abnormalities in cells, which may predispose supplement-takers to developing cancer, according to a new study.



New understanding of stem cells

In findings that could one day lead to new therapies, researchers have described some striking differences between the biochemistry of stem cells versus mature cells.



Hormone sensitivity of breast stem cells

Researchers have discovered that breast stem cells are exquisitely sensitive to the female hormones oestrogen and progesterone, a finding that opens the way for the development of new preventions and treatments for breast cancer.



For stem cells, practice makes perfect

Researchers have found that reprogramming is imperfect in the early stages of differentiation, with some genes turned on and off at random.



Better way to track stem cells

Using Indocyanine Green to label human embryonic stem cell-derived cardiomyocytes substantially improved efforts to optically track stem cells after transplanting them into heart tissues.



Keeping skeletal stem cells ‘young'

Scientists showed in mice that a molecule called Notch, which is well known for the influence it wields on stem cells that form the blood and the nervous system, is a key factor in the development of mesenchymal stem cells.



Growth factor promotes stem cell growth

Scientists have identified a new growth factor that stimulates the expansion and regeneration of hematopoietic stem cells in culture and in laboratory animals.



Stem cell function characterised

A team of researchers are the first to fully characterise a special type of stem cell, endothelial progenitor cells, that exist in circulating blood, to see if they can behave as endothelial cells in the body when cultured on a bioengineered surface.



Birth of blood-forming stem cells in embryo

Biologists at UC San Diego have identified the specific region in vertebrates where adult blood stem cells arise during embryonic development.



Technique make stem cells pluripotent with ease

Tiny circles of DNA are the key to a new and easier way to transform stem cells from human fat into induced pluripotent stem cells for use in regenerative medicine.



Biodegradable structure for stem cell growth

Medical researchers were shocked to discover that virtually all human embryonic stem cell lines being used in 2005 were contaminated.



Novel theory for mammalian stem cell regulation

A paper proposes a model of mammalian adult stem cell regulation that may explain how the coexistence of two disparate stem cell states regulates both stem cell maintenance and simultaneously supports rapid tissue regeneration.



Spices halt growth of breast stem cells

A new study finds that compounds derived from the spices turmeric and pepper could help prevent breast cancer by limiting the growth of stem cells.



Keeping stem cells poised for action

Researchers have identified a critical component that recruits other regulatory proteins to genes important in differentiation and also modulates their activity to keep them in a state of ongoing readiness.



Stem cell transplantation treat advanced leukemia

Researchers have reported the use of a radio-labeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients.



Mechanical forces impact stem cells

Applying a small mechanical force to embryonic stem cells could be a new way of coaxing them into a specific direction of differentiation, researchers at the University of Illinois report.



Making better stem cells

Scientists has developed a method that dramatically improves the efficiency of creating stem cells from human adult tissue, without the use of embryonic cells. The research makes great strides in addressing a major practical challenge in the development of stem-cell-based medicine.



World will miss 2010 target to stem biodiversity loss

The world will miss its agreed target to stem biodiversity loss by next year, according to experts convening in Cape Town for a landmark conference devoted to biodiversity science.



Genetics: How stem cells make skin

An international team of researchers have discovered two proteins that control when and how these stem cells switch to being skin cells.



Enhancing stem cells power

Researchers have shown for the first time that light energy can gently guide and change the orientation of living cells within lab cultures.



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