Examining the light scattering behaviour of known promiscuous inhibitors

How a rapid method for detecting non-specific small molecule aggregation can facilitate compound screening

Scientists identify molecular trigger for Alzheimer’s disease

New research establishes nature of malfunction in protein molecules that can lead to onset of dementia.

But what does it do?

Most complete database to date of human phosphatases and their substrates

Study identifies “chink in the armour” of Schmallenberg virus

A key building block in the Schmallenberg virus could be targeted by anti-viral drugs, according to a new study led from the University of Leeds.

‘Next generation’ cancer drug shows promise in early trial

A new potential cancer drug has shown promising results in an early stage clinical trial. The drug, called AUY922, could help lead to a new way to treat a wide range of cancers including breast and lung cancer.

Detecting sub-nanometre molecules at low concentrations

W130i dynamic light scattering system delivers 'outstanding' performance from only microlitres of sample in seconds

Turning molecules into super protein killers

Using a novel light activation technique, scientists have been able to turn molecules with only a modest ability to fight specific proteins into virtual protein destroyers.

Generating RNA molecules in water

Researchers in Italy have reconstructed one of the earliest evolutionary steps yet: generating long chains of RNA from individual subunits using nothing but warm water.

Synthetic molecules trigger immune response to HIV

Researchers have developed synthetic molecules capable of enhancing the body's immune response to HIV and HIV-infected cells, as well as to prostate cancer cells.

Computer predicts reactions between molecules and surfaces

Good news for heterogeneous catalysis and the hydrogen economy: computers can now be used to make accurate predictions of the reactions of molecules with surfaces.

DNA molecules in moss opens doors

Plasmid-based methods, which had been limited to single-cell organisms such as bacteria and yeasts, can be extended to mosses, opening the door to applications of a number of powerful techniques in plant research.

Previously invisible molecules seen for the first time

A room-temperature technique allows researchers to identify previously unseen molecules in living organisms and offers broad applications in biomedical imaging and research.

Encasing single molecules in microdroplets

Inventing a useful new tool for creating chemical reactions between single molecules, scientists have employed microfluidics to make microdroplets that contain single molecules of interest.

Discovery to aid study of biological molecules

Researchers have discovered that a tool widely used in nanoscale imaging works differently in watery environments, a step toward better using the instrument to study biological molecules and structures.

Small molecules mimic natural gene regulators

In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should.

Particles, molecules prefer not to mix

Scientists used computer simulations to study a very simple model of molecules on surfaces, which looks a lot like the computer game Tetris.

Small molecules might block mutant protein

Molecules that selectively interfere with protein production can stop human cells from making the abnormal molecules that cause Huntington's disease.

Sticky molecules

Chemists have designed an organic molecule that binds negatively charged ions, a feat they hope will lead to the development of a whole new molecular toolbox.

Big, sticky molecules

The artificial spider silk production exemplified the expertise and skills required for successful applications in biosupramolecular chemistry.

Imprisoned molecules 'quantum rattle' in their cages

Scientists have discovered that a space inside a special type of carbon molecule can be used to imprison other smaller molecules such as hydrogen or water.






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