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Locked nucleic acid fluorescent probes provide novel alternative

Locked nucleic acid is a promising and powerful technology for real-time quantitative polymerase chain reaction.



Locked nucleic acid ­ high affinity nucleic acid analogues

Locked nucleic acid (LNA) forms exceptionally thermostabile duplexes with complementary DNA and RNA and has the potential to improve current in vitro DNA diagnostic technologies and therapeutic drug development. Report by Jan Skouv, Henrik Ørum and Mogens Havsteen Jakobsen.



Locked nucleic acid ­ a new tool for in vitro DNA diagnostics

Locked nucleic acid (LNA) forms DNA- or RNA-heteroduplexes with exceptional high thermal stability, and has the potential to improve current in vitro DNA diagnostic technologies. Jan Skouv, Nana Jacobsen and Mogens Havsteen Jakobsen report the latest research and what is likely to be the impact on today's and tommorow's technologies.



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