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Orphan Drug Congress 2012

As rare diseases affect only a tiny group of people, pursuing the development of treatments has traditionally not been attractive for pharma companies. In order to discuss major concerns, the newest solutions and challenges, Fleming Europe has organized its 2nd Annual Orphan Drug Congress 2012, taking place 17 – 18 October in Spain.



Considerably more patients may benefit from effective antidiabetic drug

The antidiabetic drug metformin is not prescribed for patients with reduced kidney function because the risk of adverse effects has been regarded as unacceptably high. A study has found that the risks have been substantially overrated. As a result, many more patients with diabetes may be able to enjoy the benefits of the medication.



Alzheimer's drug fails to reduce significant agitation

A drug prescribed for Alzheimer’s disease does not ease clinically significant agitation in patients with Alzheimer’s disease, according to a new study led by the University of East Anglia (UEA).



New drug to tackle fat problems

Medical researchers at the University of Sheffield have defined the structure of a key part of the human obesity receptor- an essential factor in the regulation of body fat- which could help provide new treatments for the complications of obesity and anorexia.



Innovative screening tools accelerate drug discovery

Exclusively available in the UK from Cambio, Transcreener® HTS Assays and iuvo Microconduit array technology meet a demand for high performance tools which will speed discovery of new therapies.



Treating drug addiction with nanoparticles

A precise, new nanotechnology treatment for drug addiction may be on the horizon as the result of research conducted at the University at Buffalo.



Accelerating the drug discovery process

The Maybridge Quick2Lead Compound Kits are designed to save time and money by enabling rapid compound library synthesis around bioactive "hits" emerging from screening assays.



Potential pathway for drug intervention

A newly identified molecular pathway that directs stem cells to produce glial cells yields insights into the neurobiology of Down's syndrome and other disorders.



Drug blocks deadly viruses

Two highly lethal viruses that have emerged in recent outbreaks are susceptible to chloroquine, an established drug used to prevent and treat malaria, according to a new basic science study.



Vegetable-based drug could inhibit melanoma

Compounds extracted from green vegetables such as broccoli and cabbage could be a potent drug against melanoma, according to cancer researchers.



Aiding drug discovery

Determining the structure of unknown natural compounds is a slow and expensive part of drug screening and development - but this may now change.



Anti-restenosis drug

A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance.



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