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Arthritis drug might fight flu

Researchers have found that an approved drug for treating rheumatoid arthritis reduces severe illness and death in mice exposed to the Influenza A virus.



Cancer drug linked to brain virus

Rituximab is the most important and widely used cancer drug for lymphoma. It is also approved for treatment of rheumatoid arthritis and is widely used off-label to treat multiple sclerosis, lupus erythematosus and autoimmune anemias.



Old diabetes drug teaches experts new tricks

Research reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar by regulating the genes that control its production.



Atypical patients in in antidepressant drug trials

One reason antidepressant medication treatments do not work as well in real life as they do in clinical studies could be the limited type of study participants selected.



Parkinson's, drug addiction link

Scientists have identified a protein that appears not only to be central to the process that causes Parkinson's disease but could also play a role in muting the high from methamphetamine and other addictive drugs.



Nanotech STD drug delivery

Researchers describe a breakthrough in safe and effective administration of potential antiviral drugs the first step in development of a new kind of treatment for sexually transmitted diseases.



Inexpensive drug relieves fibromyalgia pain

Naltrexone, which has been used clinically for more than 30 years to treat opioid addiction, was found to reduce symptoms of pain and fatigue an average of 30 percent over placebo.



Determining cancer drug responses

Researchers studying "outlier" cells in the context of a new and highly touted cancer drug have found that vastly disparate reactions occur within genetically homogeneous cell groups.



Promising prostate cancer drug

A new multi-centre study shows that an experimental drug lowers prostate specific antigen levels in men with advanced prostate cancer for whom traditional treatment options have failed.



New model for drug discovery

Chemists and anaesthesiologists have identified a fluorescent anaesthetic compound that will assist researchers in obtaining more precise information about how anaesthetics work in the body



Drug curbs urges of compulsive stealers

It appears that a drug commonly used to treat alcohol and drug addiction has a similar effect on the compulsive behaviour of kleptomaniacs - it curbs their urge to steal.



Drug for Clot Victims

Researchers have identified the mechanism that makes a bioengineered enzyme function efficiently, opening the way to clinical development of the first safe clot busting agent.



Revealing drug targets

Scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention.



Faster access to high affinity antibody drug candidates

MorphoSys AG has unveiled a multi-year technology development programme which will lead to a significantly enhanced version of its antibody generation platform.



The hottest tool in drug discovery and efficacy

Although the promise and potential still exists, we still have much to learn about the nature of stem cells. Lisa Masterson reports.



Integration of technology and software improves drug prospects

Scientific computing specialists at Genedata and ChemAxon have successfully integrated the chemical intelligence functionality of MarvinView with Hit Profiler, Genedata’s newly-released software solution for the prioritisation of hits to leads.



Drug discovery companies turn to low cost Asian countries to evade stringent regulations

The Indian and Chinese drug discovery outsourcing market is riding a crest with companies from outside Asia increasingly seeking to outsource drug discovery to these countries for greater cost savings.



FDA underlines commitment to post-marketing drug testing

Critical Path is a broad initiative at the FDA involving all of its medical centres. The effort is aimed at catalysing the creation of a new generation of scientific tools to enable product sponsors to better predict and evaluate the safety and effectiveness of candidate products.



Sensitive drug discovery

Dynamic light scattering (DLS) technologies are evolving as critical automated tools in drug discovery because it is non-invasive, reproducible and sensitive.



Early screening and innovative solutions key to drug development

The vast majority of clinical drug candidates fail during the development stage because of poor absorption, distribution, metabolism or toxicity (ADME/Tox) problems. However, new screening techniques will help to reduce attrition rates. Sean Ottewell reports.



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