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Open source innovation increasingly being used in drug discovery

New discoveries have led to the need for new ways to tap the vast amounts of information, so as to optimise its potential use



Cardialysis and Sticares InterACT announce strategic drug discovery collaboration

Both organizations have substantial experience and success in the execution of clinical research projects for pharmaceutical, biotechnology and medical device companies



Criminalisation of drugs and drug users fuels HIV

Strict laws on the criminalisation of drug use and drug users are fuelling the spread of HIV and other serious harms associated with the criminal market and should be reviewed, say experts.



A new spin on drug delivery

A diverse team of researchers have discovered how to greatly enhance the delivery of DNA payloads into cells and could revolutionize various forms of therapy.



Anti-clotting drug helps bedridden patients

A treatment plan used to prevent potentially dangerous blood clots in recovering surgical patients can also benefit some patients immobilized by acute medical illness, doctors have found in a multi-institutional study.



New strategy to fight cancer drug resistance

Scientists at Dana-Farber Cancer Institute have found a way to disable a common protein that often thwarts chemotherapy treatment of several major forms of cancer.



Hep C drug trials begin

The first clinical trials have started on a new investigational drug, discovered by researchers at Cardiff University, which is being developed to treat infections caused by Hepatitis C virus.



Traits associated with prescription drug disorders

Researchers at Boston University School of Medicine have identified clinical characteristics associated with prescription drug use disorder in primary care patients with chronic pain.



New twist on potential malaria drug target

Researchers seeking to block invasion of healthy red blood cells by malaria parasites have instead succeeded in locking the parasites within infected blood cells, potentially containing the disease.



Potential drug to combat Kaposi's sarcoma

Research from the University of Leeds has identified how the virus which causes Kaposi's Sarcoma replicates and spreads - opening a door to a possible new treatment for the disease.



Development of promising drug for inflammation

A novel anti-inflammatory drug being developed and commercialised by an inflammation expert has shown promise in relieving symptoms of inflammation, while substantially reducing the incidence of bleeding and intestinal damage often caused by NSAIDs.



Compulsive eating linked to drug addiction

In a newly published study, scientists have shown for the first time that the same molecular mechanisms that drive people into drug addiction are behind the compulsion to overeat, pushing people into obesity.



Acne drug prevents HIV in lab

Scientists have found that a safe and inexpensive antibiotic in use since the 1970s for treating acne effectively targets infected immune cells in which HIV lies dormant and prevents them from reactivating and replicating.



New cancer drug screening technique

Scientists have developed a laboratory technique that more closely simulates the real-world conditions in which tumour cells mingle with the body's normal cells.



Genes found linked to breast cancer drug resistance

Researchers have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumours that have been treated with commonly used chemotherapy drugs.



Common drug could help prevent skin cancers

A widely-available anti-inflammatory prescription drug can reduce the risk of a common skin cancer in humans, according to a researcher at Stanford's School of Medicine.



Why certain drug combinations backfire

Researchers have found that the answer lies in the way some antibiotic drugs influence a bacterial cell's gene expression levels.



1930s drug slows tumor growth

A glaucoma treatment causes luscious eyelashes. A blood pressure drug also aids those with a rare genetic disease. Now, a a gonorrhea medication that might help battle cancer.



Nanoscale drug delivery for chemotherapy

Duke University bioengineers have developed a simple and inexpensive method for loading cancer drug payloads into nano-scale delivery vehicles and demonstrated in animal models that this new nanoformulation can eliminate tumors after a single treatment.



Paradigm shift needed to combat drug resistance

When people travel, bacteria and other infectious agents travel with them. As about a billion people cross international borders each year, many more billions of the bugs come along for the ride.



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