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Drug discovery techniques focus on speed and cost reduction

Drug discovery relies on a huge range of techniques, from polymerase chain reaction analysis to clinical trial design. Here we highlight the latest innovations designed to cut costs and increase the speed of new drug discovery



Gene test could pinpoint patients sensitive to new type of cancer drug

Scientists found that defects in a gene called ARID1A caused sensitivity to new drugs targeting the DNA repair process within tumour cells



New research looks at novel ways to combat drug resistance

University of Southampton biological scientists are leading a major research project aimed at making drugs more effective.



Study proves drug success for the treatment of severe dementia

A drug commonly used to treat mild to moderate Alzheimer’s Disease (AD) can have positive benefits for patients in the later stages of dementia, research has found.



Targeted skin cancer drug launches in UK

Vemurafenib, marketed by Roche as Zelboraf, is the first personalised treatment that has been shown in clinical trials to increase survival time for patients with a specific BRAF gene mutation. The European Commission has licensed the drug for adults with this mutation whose cancer is inoperable or which has spread.



Natural products drug discovery symposium announced

Groundbreaking research into the development of new medicines from the earth’s natural resources will be the focus of a symposium in March, hosted by the University of Aberdeen.



Heptares scientist report the first use of structure-based drug design to discover GPCR-targeted drug candidate

Heptares Therapeutics, the leading GPCR drug discovery company, provides an update on recent scientific publications that highlight its unique ability to generate valuable information on GPCR structures and ligand binding.



Genevac concentrator helps sports drug testing lab accelerate sample preparation

Genevac has announced an applications report that details how its miVac Duo sample concentrator has been used by a leading testing laboratory to develop a new sample preparation method to help curb sports doping.



Half of care home patients suffer drug errors

Errors in administration of medication are a serious problem in long-term residential care. A new electronic medication management system specifically developed for use in residential and nursing homes has been shown to significantly reduce drug administration errors, according to UWE Bristol and University of Warwick.



Drug screening assays in living zebrafish disease models

Microplate reader systems enable development of in vitro and in silico assays that allow high throughput screening



Future growth areas for drug delivery device industry

Report identifies opportunities and threats faced as markets change radically over the next 10 years



UK-discovered prostate cancer drug launched in Britain

Treatment for prostate cancer works by blocking synthesis of testosterone in all tissues including the tumour itself



Use of hyaluronic acid to extend drug release in osteoarthritis applications

Novozymes Biopharma to present latest advances in drug delivery technology at Controlled Release Society Meeting



Hitting moving RNA drug targets

RNA now is understood to perform a number of other vital roles in the cell



Fragment-based drug discovery

Heptares deploys StaRsR to unlock the power of fragment screening for intractable GPCR drug targets



Filters for safe liquid filtration of injectable drug products

Filters have been tested for and meet United States Pharmacopeia 788 as well as Federal Drug Administration Title 21, Section 211.72 regulation



Solving the solvent mystery for better drug design

Scientists have been able to watch a chemical reaction happening in solution with more detail than ever before



Prototype drug targets metabolism, halts disease that limits bone marrow transplantation

Findings challenge a long-standing model of how activated cells of the immune system make ATP, opening the door for fundamentally new approaches to combat immune diseases



Importance of nanotechnology in formulation and drug delivery

Conference will provide a forum for industry professionals to discuss and highlight and to encourage collaborative working



New strategies for cancer drug development urgently needed

Millions of cancer patients may soon be able to receive more personalised treatments thanks to developments in the understanding of cancer biology



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