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Identifying genes in lung fibroblasts

Ludger Altrogge, Lubna Hussain and Rochelle Myers report on asthma- and COPD-related differential gene expression in primary human lung fibroblasts



On the road to prevention and healthy living

European Academy of Allergy and Clinical Immunology (EAACI) celebrates 60 years at the forefront of allergy science and patient care



Understanding the effects of genes on human traits

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia.



Public to see impact of medical research funding

Europe’s largest store of open-access biomedical literature has joined forces with a leading online research outcomes system to connect research articles and grants with data on their impact.



Study finds nearly 5 million asthmatics worldwide could benefit from antifungal therapy

An estimated 4,837,000 asthmatics with allergic bronchopulmonary aspergillosis (ABPA) could benefit substantially from antifungal treatment, say researchers from the University of Toronto and Manchester University.



Size of baby in womb as an indicator of childhood asthma and allergies

Children with asthma at five and 10 years had been 5mm or 10 per cent smaller than average as 10 week old embryos



A natural fruit compound may help asthma

Researchers found a compound from a New Zealand blackcurrant may reduce lung inflammation with a multi-action assault in allergy-induced asthma.



H1N1 influenza vaccine trial in people with asthma

The NIH is preparing to launch the first government-sponsored clinical trial to determine what dose of the 2009 H1N1 influenza vaccine is needed to induce a protective immune response in people with asthma.



Adults with asthma not getting their flu vaccinations

Investigators have determined that the vaccination levels among adult asthma sufferers falls well short of suggested guidelines.



Treating allergy-induced asthma

Scientists for the first time identified the ion channel TRPA1 as playing an essential role in allergic asthma and demonstrated that Hydra's TRPA1 antagonist HC-030031 effectively treated allergic asthma in mice.



Vitamin D levels linked to asthma severity

Serum levels of vitamin D were inversely linked to several indicators of allergy and asthma severity, including hospitalisations for asthma, use of inhaled steroids and total IgE levels.



No asthma relief

A new study of adults with inadequate asthma control without significant heartburn shows that heartburn medication does not help control their asthma symptoms.



Experimental models of asthma

Over the years the topics have ranged from methodological aspects to the influence of infections and environmental factors up to perspectives in the development of new therapeutic strategies.



Strategies for the identification of new asthma targets

Over the last decade mouse models of experimental asthma proved to be a valuable tool for the investigation of mechanisms that underlie acute allergic airway inflammation.



Allergen levels and asthma

Results from a new survey demonstrate that elevated allergen levels in the home are associated with asthma symptoms in allergic individuals.



Modern living leads to an increase in asthma sufferers

Asthma is one of the most common respiratory diseases worldwide. During an asthma attack, the airways become constricted, leading to symptoms ranging from wheezing and coughing to severe shortness of breath.



Yin and yang of asthma

The allergen breathed in by a person with asthma triggers a proteinase or enzyme called MMP7 that activates a cascade of events to prompt an allergic reaction.



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