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In vitro cell models for cortical neurophysiology

12th June 2014


AMSBIO offers an extensive range of iPSC derived neural cells including normal and Alzheimer's disease neural progenitor cells, and cerebral cortical neurons.

These neural cells are derived using integration-free, fully defined neural induction conditions.

AMSBIO neural cells

AMSBIO neural cells are capable of generating a spectrum of cortical neurons that are electrically active and have the ability to form functional synapses and circuits in vitro.

Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer's disease, autism, epilepsy and stroke. Despite strong interest in these diseases, high quality human in vitro cell models for cortical neurophysiology were unavailable until now.

AMSBIO also offer a complete suite of cell reprogramming and neural differentiation services to meet your neural research needs.

For cell reprogramming simply provide us with your patient/donor skin fibroblasts, blood cells or iPS cells and we will take care of the rest. After you receive the neural progenitor cells and/or functional neurons from us, AMSBIO will also provide ongoing support to facilitate adaptation of the neural cells in your experimental systems. Deriving, maintaining and differentiating iPS cells is a time consuming and labour intensive process, especially when you are dealing with multiple lines. 





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