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Robust multiplexing

6th June 2017

Posted By Paul Boughton


Integrated DNA Technologies (IDT) has announced a broad partnership with Illumina to provide improved library preparation multiplexing and target enrichment solutions for the next generation sequencing (NGS) market.

The agreement will see IDT and Illumina leveraging their expertise in the genomics field to deliver enhanced tools for sequencing.

Under the partnership, the companies will develop a portfolio of indexed adapters to be manufactured by IDT.

Specifically designed for multiplex NGS, the indexed adapters contain new sample index sequences, optimised for use on Illumina systems, including two-channel, patterned flow cell systems, such as the NovaSeq series.

These novel indexed adapters will extend the number of unique dual indexes (UDI) from 8 to 24, allowing higher sample multiplexing capabilities with improved data quality.

The companies intend to further expand to 96 UDI kits in Q4 of 2017.

Further, the optimised index codes will be available now via IDT for incorporation into custom third party NGS library prep adapter sets.

The partnership also includes a co-marketing agreement whereby the companies will provide a complete workflow for exome capture.

This arrangement couples Illumina’s TruSeq and Nextera library prep kits with the industry’s best performing exome capture panel, IDT’s xGen Exome Research Panel.

Users will benefit from more flexible, high quality solutions for whole exome sequencing and improved customer technical support as a result of the combined offering.





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