Modular NGS gene capture pools launched

Integrated DNA Technologies (IDT) has announced the introduction of xGen predesigned gene capture pools and plates. These modular gene capture probes are the latest addition to IDT’s growing portfolio of high quality, customisable sequencing products.

The xGen range is ideal for creating customised target capture panels for enrichment of 10 or more genes or for enhancing the performance of existing panels. Predesigned gene capture pools and plates are ideal for scientists who need to reduce the cost of their NGS experiments without sacrificing quality and specificity. xGen predesigned gene capture pools are available for the coding regions of any human RefSeq gene and are delivered premixed in tubes or in individual plate wells for selective mixing.

NGS target capture technologies have previously been available mostly as either fixed, off-the-shelf probe pools or panels that do not always meet experimental needs or expensive custom panels. With xGen, researchers and core labs can now generate relevant, custom gene panels in-house. Individual and core labs can also distribute the cost of custom target capture panels by ordering the probes in plates and mixing genes as necessary for each researcher. This customisation allows smaller starting volumes per panel, resulting in less waste.

Rami Zahr, NGS product manager at IDT, said, “With xGen predesigned capture gene pools and plates, researchers will not have to choose between ability to customise and cost. Additionally, they will be able to get the relevant sequencing data they need more efficiently. This product represents another step made by IDT toward making sequencing more affordable and more practical for a wider range of applications.”

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