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Controlled synthesis of active ingredients

18th December 2018


Syrris Orb delivers controlled synthesis of active ingredients
 

An Orb jacketed reactor from Syrris is helping Italian company NIS Materials to reproducibly synthesise new materials used as active ingredients for products such as paints, polymeric coatings and concrete. Marco Marchetti, founder and CEO, explained: “Currently, we do a lot of work with the building and construction sector, synthesising active ingredients with specific properties – for example, antibacterial or anti-odour products – for use in paints and coatings. Moving forwards, we plan to use our background in biomaterials to expand into biomedical applications. Reproducible synthesis depends on strict control of reaction parameters such as pH, temperature, time and rate of reagent addition, which can all affect the properties of the active ingredient. It is particularly important to control the reaction pH, temperature and stirring, since even slight changes can compromise the end product.
 
“The Orb is easy to set up and use, and offers exceptional control of pH and other reaction parameters, enabling us to continuously optimise our processes. To increase the level of automation, we use the Orb with a Syrris Atlas syringe pump and a Reactor Master module – a user-friendly device that allows us to set up reactions, store and analyse experimental data, and compare different synthesis profiles. We also have the Reactor Master PC software for occasions when full PC control is preferred. I am very satisfied with the Orb. It offers the control and reproducibility that is vital to all of our experiments, and is the best system in the marketplace.”

 





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