Sartorius Stedim Biotech and Refine Technology announce cooperation

Goettingen, Germany | Pine Brook, NJ, USA, January  2012 /  B3C newswire - Sartorius Stedim Biotech (SSB), a leading international pharma supplier, and Refine Technology the developer and worldwide supplier to the biotech industry of the ATF™ System, a best-in-class cell retention device, will be collaborating on the development of a robust platform for high-density cell cultivation. This platform will enable fast, easy connection of the ATF System to SSB’s  field-proven single-use BIOSTAT® bioreactors.

 This joint development project proactively responds to the current  market demand for more effective connectivity between equipment from  different suppliers to enable development of efficient, streamlined  systems. “We decided to work together, based on market feedback, to create  a better platform for late-stage clinical and commercial-scale  biopharmaceutical manufacturing processes. Our objective is to give our  customers the confidence of a well-thought-out system featuring optimal  and robust high-density cell cultivation via perfusion and concentrated  fed-batch processes,” stated Christel Fenge, Vice President of  Fermentation Technologies at SSB.

 “The market demand for cell retention systems is expanding rapidly and  we are pleased to be working with Sartorius Stedim Biotech to ensure that  the ATF System integrates effortlessly with the BIOSTAT bioreactors. Our  objective is to dramatically reduce the risk and cost of upstream  processing through continuous culture and process intensification,”  explained John Bonham-Carter, Vice President of Sales and Business  Development at Refine.

 As a first step, Sartorius Stedim Biotech and Refine are now providing  users with initial application and protocol guidance for connecting the SSB single-use and reusable bioreactors and Refine’s ATF System on the  following websites: and In the future, both companies will work closely together, along with  customers, to provide improved automation and process operation.

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