The kit is based on a novel capture concept that allows for the reversible capture of biotinylated molecules and generic regeneration. The sensor chip, Sensor Chip CAP, is built on a carboxymethylated dextran matrix to which a ss-DNA molecule is pre-immobilized. Biotin CAPture Reagent consists of streptavidin conjugated with the complementary ss-DNA molecule.
The kit is available in two versions, Biotin CAPture Kit and Biotin CAPture Kit Series S, one for each sensor chip format used in Biacore systems. The kit is compatible with most samples and analytes, and the majority of applications and analyses, performed using Biacore systems.
The new Biacore X100 2.0, due to be launched in September, includes a built-in pre-programmed workflow to support the kit.