Milligram quantities of highly purified Phospho-specific polyclonal antibodies are available from AMSBIO (www.amsbio.com) custom designed for optimal recognition of specific phosphorylation sites on the protein of interest to research scientists.
Phosphorylation events are integral to cellular regulation functions including activation of enzymes and receptors, cellular transcription, signal transduction and cell signaling networks. Custom phospho-specific antibody production can ensure that the peptide mimics the natural conformation and activity found in the protein. Phosphorylation often results in functional changes in the activity of a protein, and having antibodies recognising the phosphorylated state (as well as the corresponding non-phosphorylated state) can be integral for studying protein pathways.
Drawing upon many years experience AMSBIO has developed a custom phospho-specific antibody production service that is both reliable and produces high quality product. Following peptide synthesis, conjugation, immunisation and anti-sera production all antibodies are purified using a double column immuno-affinity method. The purified phospho-specific antibody is then fully characterised using both dot-blot and ELISA techniques.
Further information on AMSBIO custom phospho-specific polyclonal antibodies may be downloaded from http://www.amsbio.com/newsdetail.aspx?newsID=57
Founded in 1987, AMS Biotechnology (AMSBIO) is recognised as a leading international provider of unique & innovative products & custom services for life sciences research. The AMSBIO range includes over 23,000 polyclonal & monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, & tissue DNA, RNA, protein & microarray products. Key research areas include: apoptosis, cell invasion & migration, cell signalling, DNA damage, electrophoresis, glycobiology, posttranslational modification & stem cell biology.
