Enhancing productivity in preparative separation of enantiomers

The separation of enantiomers by chromatography is a field expanding significantly due to the increasing interest for pure enantiomers in the pharmaceutical industry.

Sequential isolation of plasma proteins aids immunoglobulin yields

The demand for immunoglobulin is high and is predicted to rise. John Curling reports that current goals are to improve yield of immunoglobulin while maintaining product quality.

chromatography data system

Autoscribe Ltd's Varian Galaxie chromatography data system is now available. Galaxie is fully scalable from single chromatograph workstations to global implementations with an easy upgrade path.

The case for contracting analytical physicochemical profiling services

A physicochemical profile is important for predicting drug absorption, disposition and transport. This involves measuringa number of properties which many laboratories are ill-equippedto handle. One solution is to use contract analytical...

Multi-compound LC-MS-MS analyses

Waters Corporation's latest version of QuanOptimise is an enhanced plug-in for the market leading Mass-Informatics platform (MassLynx 4.0).

Affinity chromatography is vital to protein research and development

Because they are derived from living organisms, biological products present a potential source of pathogens. By John M. Curling.

Ultrasonic spectroscopy moves into laboratory for dynamic monitoring

Ultrasonic spectroscopy is all set to become a routine analytical technique in the laboratory. It provides a non-destructive way to measure the properties of materials, using sound waves rather than the more usual electromagnetic waves. As...

Use of hydrogen generators to supply the gas for laboratory use is on the increase

The use of hydrogen generators to supply hydrogen for laboratory use is becoming increasingly widespread.

Sample purification kits for mRNA and protein

Now available from Bio-Nobile Oy is a range of kits for the purification of nucleic acids and proteins, based on BN's magnetic particle separation technology.

launch of

The life sciences are some of the fastest moving industry sectors around today. Technologies, techniques and strategies develop, change and move on at bewildering speed.

Storing and sharing analytical data for maximum commercial benefit

Data-mining, viewing and comparison of data across the organisation are just a few of the issues surrounding the archival of analytical data to facilitate knowledge management. Here, Kevin Smith examines the issues in depth and introduces a...

affiline platform technology

For the design of artificial antibody-like binding proteins ­ the Affilines ­ Scil Proteins is developing the proprietary Affiline Platform Technology.

Imaging crystalline protein grains in 3D using X-ray diffraction

Preparing protein crystals has always been difficult because their growth mechanisms are not well understood. A better insight into these mechanisms is now possible, using a new imaging method based on coherent x-ray diffraction.

broad selectivity and high loading capacity of csps

Over the past 20 years the interest in developing more and more single enantiomeric drugs has grown tremendously since it has been demonstrated that the stereochemistry of such active substances is one of the major factors determining their...

Rapid sample analysis while maintaining resolution of components

Quadrex Corporation's range of non-polar PHAST GCTM columns with 0.10mm and 0.18mm I.D.s but with films up to 3.5microns thick. These PHAST GCTM columns allow for rapid sample analyses while maintaining ideal resolution of components.

Fast and flexible capillary electrophoresis

Organic acids and anions are essential molecules in environmental and biological processes. Their determination is important for the food, pharmaceutical and other industries for quality control as well as for research purposes.

Development in high-speed optical transmission systems

Even in the current economic downturn, the internet continues to experience exponential growth in data traffic. In order to accommodate and promote this growth we need not just higher capacity systems but ones that significantly reduced...

Affinity chromatography is focal point in proteomics techniques

John Curling reports on the use of affinity chromatography in protein research and development.

Proteomics goes on the march and outstrips computerised systems

Eric Russell looks at the technical advances in genomics and proteomics which have spawned a related revolution in the growing field of bioinformatics. This can be described as the acquisition, analysis, and storage of biological...

SPR-based instruments for molecular binding studies

Surface plasmon resonance enables the detailed study of biomolecular function in real time and without the need for fluorescent tags or radioactive markers, and often without the need for prior purification. Elab reports.




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