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X-rays view nanoscale

Scientists have developed a lensless X-ray technique that can take images of ultra-small structures buried in nanoparticles and nanomaterials.

Kidney drugs promoted

Before a CT scan or angiogram, many people should take inexpensive drug to protect kidneys because agents that enhance the scans can harm vulnerable kidneys.

High-purity skids

In order to meet critical production requirements for a clinical trial of a new treatment for Pompe disease, high-purity skids for use in...

Checking polymorphic changes in filled chocolates

The consequence of the polymorphic nature of cocoa butter is that, when used in chocolate, the chocolate needs to be tempered in order to crystallise the cocoa butter in one of the stable forms – bV or bVI.

Protocols for sample preparation and analysis

To assist with proteomics research, Pall Life Sciences has developed a detailed application handbook containing a range of protocols for sample preparation and analysis.

Mass spectrometry

High-definition mass spectrometry system and a linear ion trap mass spectrometer feature electron transfer dissociation technology 

Standard file formats – taking mass spectrometry a step forward

Standard file formats are critical when immediate and easy access to a range of raw instrument data is required.

Application software for LC/MS portfolio

Agilent Technologies has introduced new application software for its 6000 Series portfolio of liquid chromatograph/mass spectrometer (LC/MS) systems.

Immobilised Chiral columns can be used with any solvents

Dr Brian Freer looks at a new range of immobilised Chiral columns.

New ion trap mass spectrometer boosts protein characterisation

Anew ion trap liquid chromatograph and mass spectrometer (LC/MS) that allows scientists to study proteins in a manner that was previously achievable only on a million-dollar floor-standing instrument that requires a dedicated operator.

Streamlined performance and validation with digital automation

Two new projects in Bulgaria and Norway have shown how digital automation technology can increase production, streamline validation and...

Application guide helps to find the right chiral separation approach

When faced with a new chiral molecule the chromatographer has to find the right column to quickly and reliably separate enantiomers.

High-purity skids used in trials for biopharmaceutical production

In order to meet critical production requirements for a clinical trial of a new treatment for Pompe disease – and help save the lives...

Biotechnology-driven therapies boost innovative treatments

Across Europe, biotechnology is driving advances in new therapies. Sean Ottewell outlines three of the latest innovations to tackle human...

Rapid and reliable test

Rapid screening test kits have many benefits in comparison to traditional testing methods for determining the presence of antibiotics in honey.

LC-MS/MS in the hunt for ‘illegal’ dyes in foodstuffs

The use of non-permitted (‘illegal’) dyes for colouring foodstuffs first came to public attention during May 2003 and resulted in
the largest ever food recall in UK history. This situation has presented an increasing...

Modular system for high-throughput protein purification

After completion of the human genome project, proteomics research has increasingly attracted the attention of the scientific community. However, progress in this field has been restrained by the difficulties encountered in isolating and...

Fast and specific HSA and IgG depletion for improved biomarker detection

The analysis of the complete proteome is a major interest of many researchers. Of particular importance are human bodily fluids such as serum or plasma due to their ease of accessibility and their potential for the identification of disease...

Microdosing trials point the way to smarter drug development

The last thing drug companies need now is an increase in time consuming and expensive clinical trials. But ongoing problems with Cox-2 inhibitors ­ and others ­ mean that regulators are likely to make just such a demand. At the same...

Digital multimodal imaging for biomarker detection

Darlene Wood reports on the use of charged-coupled device imaging systems in life science research imaging applications.

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