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Software processes mountains of genome data

New software is one of a new breed of computer programs able to accurately process the mountains of genome data flowing from the latest generation of gene decoding machines

Brain development

Scientists have identified a gene that, in mice, is critical for these stem cells to divide correctly. Without it, they fail and die.

Stroke brain cell damage

Researchers have identified a key player in the killing of brain cells after a stroke or a seizure - the protein asparagine endopeptidase.

Numbers not enough

Researchers are not contradicting the theory that it is possible to demonstrate signal transfer in proteins using statistical methods.

Blood test replacement

One day soon patients may spit in a cup, instead of bracing for a needle prick, when being tested for cancer, heart disease or diabetes.

Virus detection and identification

PCR-based detection and identification of viruses assumes a known, relatively stable genome.

Genotyping of Bacillus anthracis and Yersinia pestis

Anthrax and plague bacteria are etiological agents for worldwide zoonotic diseases and are considered among the most feared potential bioterror agents.

Microbial evolution

A mathematical approach for analysing a protein simultaneously in a set of ecologically distinct species to identify occurrences of natural selection has been developed.

Watching bleomycin

Researchers have created the first three-dimensional image of how a well-established chemotherapy agent targets and binds to DNA.

Scans spot hidden tumours

Full-body PET/CT scanning can detect unsuspected, treatable tumours in 3 of 15 patients with Li-Fraumeni syndrome, a rare genetic cancer disease.

Tobacco carcinogen KO

Silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves.

Muscle fibre death

An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage.

Parasitic worm disease

A research team has identified chemical compounds that hold promise as potential therapies for schistosomiasis, a parasitic disease that afflicts people worldwide.

Inflammatory diseases

Investigators have identified a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis.

Job's syndrome insights

Scientists have made another major breakthrough in understanding a rare immune disorder called Job's syndrome.

Origin of sex chromosomes

There are great similarities between the parts of DNA that determine the sex of plants and animals and the parts of DNA that determine mating types in certain fungi.

Microbial profiles of ecosystems

A new study provides the first inventories of microbial capabilities in nine very different types of ecosystems, ranging from coral reefs to deep mines.

Atherosclerosis protection

Scientists have identified the genes that bring about the reduction of "bad cholesterol" in the blood.

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