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Discovery of molecular pathway of Alzheimer's disease reveals new drug targets

The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer’s patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease.

Queen’s scientists in new bid to develop anthrax vaccine

Scientists at Queen’s University Belfast are aiming to help counteract the threat of bioterrorism by undertaking new research to develop a vaccine against anthrax.

Novartis drug Aclasta® study

Novartis has announced that the New England Journal of Medicine (NEJM) published results from a study which found that once-yearly Aclasta® (zoledronic acid 5 mg) significantly reduced the risk of spine fractures by 67% versus placebo over...

Roche medicine Avastin receives EU approval

Roche has announced that the European Commission has approved Avastin (bevacizumab) in combination with standard chemotherapy as a treatment for women with first recurrence of platinum-sensitive ovarian cancer.

Neutrons help explain why antibiotics prescribed for chemotherapy cause kidney failure

Neutron scattering experiments have provided new insights into the origin of the side effects of an antifungal drug prescribed all over the...

Vitamin variants could combat cancer as scientists unravel B12 secrets

In a development that may lead to new drugs to treat cancer, scientists at the University of Kent have discovered the process by which a key vitamin (B12) is made in cells.

Going for gold: chemists find new way to create building blocks for drugs

A new way to prepare biaryls - compounds that are essential building blocks in the creation of drugs and many modern materials such as LEDs - using gold as a catalyst is described by researchers from the University of Bristol in a recent...

Mutant parasite could stop malaria in its tracks

University of Nottingham Malaria experts have found a way of disabling one of the many phosphatase proteins which breathe life into the malaria parasite.

Orphan Drug Congress 2012

As rare diseases affect only a tiny group of people, pursuing the development of treatments has traditionally not been attractive for pharma companies. In order to discuss major concerns, the newest solutions and challenges, Fleming Europe...

New component of cannabis discovery could lead to better treatments for epilepsy

Scientists at the University of Reading have demonstrated for the first time that a previously unstudied chemical in cannabis could lead to more effective treatments for people with epilepsy.

Breakthrough in Alzheimer’s Research

A drug used by diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer’s, a study by scientists at the University of Ulster has revealed.

Possible new therapy for the treatment of a common blood cancer

Research from Karolinska Institutet in Sweden shows that sorafenib, a drug used for advanced cancer of the kidneys and liver, could also be effective against multiple myeloma. The disease is one of the more common forms of blood cancer and...

Considerably more patients may benefit from effective antidiabetic drug

The antidiabetic drug metformin is not prescribed for patients with reduced kidney function because the risk of adverse effects has been regarded as unacceptably high. A study has found that the risks have been substantially overrated. As a...

Scientists can now block heroin, morphine addiction

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

Roche / Avastin study

Roche study showed that adding Avastin to radiation and chemotherapy significantly extended the time people with an aggressive form of brain cancer lived without their disease worsening.

Rising to the challenge of EVMPD

Sean Ottewell looks at the latest information management systems to administer new requirements concerning the collection, reporting, coding...

Study shows Avastin has similar effect to Lucentis

The one year results from a study into whether two drug treatments (Lucentis and Avastin), are equally effective in treating neovascular or wet age-related macular degeneration (wet AMD), have been reported at an international research...

Neuroscientists discover key protein responsible for controlling nerve cell protection

A key protein, which may be activated to protect nerve cells from damage during heart failure or epileptic seizure, has been found to regulate the transfer of information between nerve cells in the brain. The discovery, made by...

Bristol researchers solve 70 year old mystery

Chemists and biologists from the University of Bristol have finally cracked one of the longest standing chemical mysteries. In a paper published today in PNAS, the team demonstrate exactly how an unusual class of compounds known as...

Discovery paves way for improved pain-killers

An international team of researchers has made a major discovery that could lead to more effective treatment of severe pain using morphine.

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