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Evaporative light scattering detection: indicator of a mass response in LC work

Evaporative light scattering detection (ELSD) has become well established in the field of liquid chromatography (LC), writes Jeanie Watkins.

New column technologies for HPLC and LC/MS

Thermo Hypersil-Keystone, manufacturer of Hypersil silica, has compiled its range of HPLC column designs and HPLC silica phases into a new catalogue.

Analytical solutions for bioproduct characterisation problems

The structural characterisation of biotechnology products presents a challenge for modern analytical techniques. In contrast to small molecule drugs, biopharmaceuticals can be extremely large, complex entities, often comprising of multiple...

Clear sample solutions in analysis of fruit and vegetable juice

Dr Achim Gessler looks at the problems associated with control and monitoring during the process analysis of fruit and vegetable juices.

Analytical HPLC chromatography offers improvements in productivity

Today the demands of separation devices are higher than ever before. Increasing productivity in high performance liquid chromatography (HPLC), through higher sample throughput and reduced analytical time, is one of the major challenges with...

Organic/inorganic solution for HPLC separation problems

High-efficiency silica-based packings have been used in high performance liquid chromatography (HPLC) since 1973. Over the past 27 years, says Sylvie Mamon, many improvements have been made to the technology of these packings.

Comparison of NIRS techniques to determine caffeine content in tea

Near-infrared spectroscopy (NIRS) is an analytical tool that is used in many different fields, and many applications have already been described in the areas of agriculture, foodstuffs, cosmetics and pharmaceuticals. Here, Angela Schmidt,...

Quantitative assay of tablets by transmission FT-NIR spectroscopy

In the pharmaceutical industry quality control is one of the most time-consuming activities in the production workflow. Kent T Møller, Magnus Tolleshaug and Thomas W. Jensen report on the use of near infrared spectroscopy for quality...

Customer service and logistics are key to clinical trial sample analysis

The pharmaceutical industry is an international marketplace. With dedicated central laboratories in the UK and US, alliances in Asia, South Africa and Australia, CentraLabS can offer a truly global service. By Dr Daniel Chapple.

ft-ir microscopy can help identify hit-and-run vehicles

For many applications in the areas of forensics, pharmaceuticals, life sciences and semiconductor development it is essential to analyse two-dimensional samples by infrared (IR) spectroscopy with high spatial resolution.

Imaging crystalline protein grains in 3D using X-ray diffraction

Preparing protein crystals has always been difficult because their growth mechanisms are not well understood. A better insight into these mechanisms is now possible, using a new imaging method based on coherent x-ray diffraction.

Affinity chromatography is focal point in proteomics techniques

John Curling reports on the use of affinity chromatography in protein research and development.

A new multipurpose research rheometer offers more flexibility

Most rheologists would prefer a rheometer that delivered state-of-the-art performance in both modes, since it would cut capital costs, and increase experimental flexibility with no performance loss. Such devices are now commercially...

High precision laboratory balances have redesigned electronics

Adam Equipment has introduced several new products to its range of weighing instruments. The company now offers a range of high precision laboratory balances ­ the AEA analytical and AEP top loading units ­ as well as the QT portable...

Surcrose: a sweet taste to mask the bitterness of pharmaceutical ingredients

Sucrose is commonly used as an excipient in oral pharmaceuticals like syrups, tablets or sachets, due to its properties. It is: soluble; anhydrous, inert, chemically, physically and microbiologically stable; available in a variety of...

New accessories for the spectrophotometer

The M400 fibre-optic diode-array UV/Visible Spectrophotometer, from Camspec, is now available with new accessories, adding enormous versatility.

spectrometer is rugged and reliable

The IR300 FT-IR spectrometer is the newest generation of the rugged and reliable instruments designed by Thermo Mattson for routine analysis. This system is suitable for environments that demand simplicity and dependability from their...

Developing mammalian cell cultures

Cell Culture Technologies GmbH, a biotech company specialising in the development and application of mammalian cell culture systems for the production of biologicals in fully synthetic, serum and protein-free culture environments.

A new source of spectrophotometric primary reference standards

NIST has produced Standard Reference Materials for calibrating the wavelength scale and verifying the absorbance accuracy of UV/Visible spectrophotometers for several decades. Recently, the NIST production capacity has become insufficient...

Food analysis

Sugars and salt determinations are two of the most commonly performed analysis in food laboratories, yet they often give cause of most concern. This is because in many laboratories these determinations are performed using traditional...

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