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Helping the brain's messengers get from A to B

A first view of shape-shifting movements in membrane transporters; hailed as a breakthrough in understanding membrane transport, research may lead to better treatments for depression and substance abuse.

Virus may trigger unusual immune cells to attack nerves

A virus infection can incite the body to attack its own nerve tissue by activating unusual, disease-fighting cells with receptors for both viral and nerve proteins.

Saliva mystery has practical impact

Researchers have solved a long-standing mystery about why some fluids containing polymers - including saliva - form beads when they are stretched and others do not.

Harnessing the immune system's diagnostic power

A team of scientists have pioneered a method for profiling the immune system, using clues provided by antibody activity to track an individual's state of health.

Understanding bacterial defence mechanisms

Scientists have combined chemistry and biology research techniques to explain how certain bacteria grow structures on their surfaces that...

Superbug's CPU revealed

A team of researchers has revealed that a small chemical, made by the superbug Staphylococcus aureus and its drug-resistant forms, determines this disease's strength and ability to infect.

Detecting cancer related enzyme

A team of researchers has developed an assay that reliably detects and quantifies mature cathepsin K using a technique called gelatin zymography.

Structure of anti-HIV immune molecule

In findings that contribute to efforts to design an AIDS vaccine, a team of scientists has determined the structure of an immune system antibody molecule that effectively acts against most strains of human immunodeficiency virus, the virus...

Predictive bio-marker for non-small cell lung cancer

For patients with non-small cell lung cancer (NSCLC), a lung cancer that kills approximately 1 million people annually, the treatment currently available is basically the same for all patients, despite the fact that some patients may...

How to avoid and respond to FDA criticisms

Ken Appel reports on how manufacturers can keep on top of regulations for temperature, humidity and controlled environments.

Orphan drugs to 'create paradigm shift'

The economic recovery process has proved difficult for the pharmaceutical industry. Factors such as patent expiry, dry pipeline, and strict...

Multiple cell types simultaneously tested

Smooth muscle cells lie at the centre of a number of pathologies throughout the body, including vascular proliferative diseases such as atherosclerosis, restenosis, vein graft stenosis, and asthma.

Overcoming anthrax's natural defences

Army scientists have discovered a way to "trick" the bacterium that causes anthrax into shedding its protective covering, making it easier for the body's immune system to mount a defence.

Resilience factor low in depression

Scientists have discovered a mechanism that helps to explain resilience to stress, vulnerability to depression and how antidepressants work.

DNA logic chips possible

Instead of silicon chips serving as the platform for electric circuits, computer engineers will take advantage of the unique properties of DNA, that double-helix carrier of all life's information.

Trapping the escape artist

Researchers recently outline how the six anti-apoptotic proteins in the Bcl-2 family are expressed differently in different cancers.

Slimming aid from the cell laboratory?

Researchers know that external influences can stimulate the production of brown fat tissue in animals. If rodents are kept at low temperatures, clusters of brown fat cells form amid the white fat tissue.

Metabolic helper fights invading viruses

Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch.

Brain's master switch is verified

The protein that has long been suspected by scientists of being the master switch allowing brains to function has now been verified by an Iowa State University researcher.

Speedier chemical reactions

A recent paper explores at a level of detail not seen before the inner workings of a chemical reaction called olefin metathesis.

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