Article Archive

Article archive

RNAi and DsiRNA: pathway, mechanism and design

Since its discovery, scientists have co-opted the RNAi mechanism as an experimental tool for studying the effects of gene silencing both in vitro and in vivo. Jaime Sabel and Hans Packer report

Improved reversed phase analysis of intact proteins

Michael McGinley, Deborah Jarret, Jeff Layne and Dirk Hansen demostrate how new core-shell particles with their engineered particle design help improve the analysis of very complex and demanding bioseparations

Automation to push molecular diagnostics markets to new level

The potential for enhanced clinical efficiency and reduced costs is fuelling the interest of healthcare stakeholders in preventive medicine. Molecular diagnostics is a vital tool to support this trend

Measuring heads for reflection measurement

The OMK ECLIPSE is the latest generation probe for the measurement of diffuse reflection

Super resolution digital microscope with automated measurements

Digital microscopy manufacturer, Keyence has released its latest microscope system, the VHX-2000

Multi-Analyte Testing

Now a growing need for rapid cost effective screening methods for antimicrobial and growth promoter compounds in matrices

Improved pumping speed with automatic evaporation

Evaporations under vacuum conditions are very demanding of pump performance and vacuum control

Never too late to debate?

Trans-Fatty Acid (TFA) in human diet is still much debated

Automation accelerates development

Accelerating the development time required for new products

Engineered cornea more resistant to chemical injury

A new study from the University of Reading has established that a prosthetic cornea made from human cells is the best model for testing how irritants and toxins cause eye injuries.

Gothenburg Team prepares for uterine transplantation

Researchers at the Sahlgrenska Academy, University of Gothenburg, are planning to conduct uterus transplants between mother and daughter. The Regional Research Ethics Committee has now given its approval and in the autumn, ten patients have been selected. The goal is that the first transplantation will be carried out before the new year.

Too much vitamin D can be as unhealthy as too little

Scientists know that Vitamin D deficiency is not healthy. However, new research from the University of Copenhagen now indicates that too high a level of the essential vitamin is not good either. The study is based on blood samples from 247,574 Copenhageners.

Single Cell Genomics

The Broad Institute and Fluidigm Corporation have announced the launch of a new research center dedicated to accelerating the development of research methods and discoveries in mammalian single-cell genomics. The Single-Cell Genomics Center is also expected to act as a hub for collaboration among single-cell genomics researchers in many pioneering fields, including stem cells and cancer biology.

SP Scientific and Praxair expand technology agreement

SP Scientific, and Praxair Inc., headquartered in Danbury, CT, are pleased to announce the expansion of their collaborative relationship to commercialize Praxair's ControLyo™ Nucleation on Demand Technology.

BAC BV launches CaptureSelect® C-tag affinity matrix for highly efficient recombinant protein purification

A revolutionary purification resin for C-terminal EPEA tagged proteins combining highly selective binding, even under denaturing condition, with mild elution of the target using the shortest affinity tag system available.

University of Nottingham to house world's first liquid X-ray machine

The University of Nottingham will be the base for the world’s first Liquid Phase Photoelectron Spectroscopy (LiPPS) machine, a high performance tool that will increase the UK’s competitiveness in a range of high-value industrial sectors including semiconductors, aerospace, pharmaceuticals and automotives.

Hepatitis C 'switch' offers target for new drug research

Scientists have discovered a 'switch' in the Hepatitis C virus which could be used as a target for new kinds of drug treatment.

Chemotherapy combined with radiotherapy increases survival in brain tumor patients

Patients with a deadly type of brain cancer could benefit from treatment in which chemotherapy is added to radiotherapy.

The environment and pharmaceuticals and personal care products: What are the big questions?

Researchers at the University of York headed a major international review aimed at enhancing efforts to better understand the impacts of chemicals used in pharmaceuticals or in personal care products, such as cosmetics, soaps, perfumes, deodorants and toothpastes (PPCPs), on the natural environment.

Structure of a retrovirus at a potentially vulnerable stage

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have for the first time uncovered the detailed structure of the shell that surrounds the genetic material of retroviruses, such as HIV, at a crucial and potentially vulnerable stage in their life cycle: when they are still being formed.

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