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Unified chromatography: the Swiss Knife of analytics

31st March 2015


Shimadzu has released the new Nexera UC SFE/SFC/MS platform combining quick and easy online sample extraction with advanced chromatographic separation and high sensitivity detection. It showcases complete automation of SFE sample pre-treatment and analysis by liquid or supercritical fluid chromatography.

The Nexera UC system is designed to fulfil the measurement requirements of a wide range of applications including: monitoring of pesticides in food products; investigation of biomarkers; additives in polymers; drug discovery in pharmaceuticals and biopharmaceuticals, environmental controls and cleaning validation, to name just a few.

The Nexera UC online SFE-SFC approach eliminates the need for tedious, manual sample pretreatment. All samples are extracted under light-shielding, anaerobic conditions, enabling highly reproducible analysis even of unstable compounds that are easily oxidised or degraded using a conventional liquid extraction method. Notably, analysis of pesticides in food products with the system and sample preparation in the SFE unit takes just a fraction of the time required when using the traditional QuEChERS method. Furthermore, the fully automated Nexera UC system offers much higher recovery rates of target analytes while significantly reducing the risk of human error during sample pretreatment. 

Nexera UC system highlights:

1. World’s first-ever unified and fully automated system combining supercritical fluid extraction (SFE) with supercritical fluid chromatography (SFC) 
2. Industry-leading sample throughput for supercritical fluid extraction, enabling up to 48 samples to be continuously and automatically processed 
3. Achieves the highest levels of sensitivity due to split-less injection of the entire volume of eluent into the mass spectrometer 






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