Article Archive

Article archive

Dear benefits for luminescence assays

Incorporating a clear cup well design the Krystal-K2 range of clear bottomed microplates from Porvair Sciences guarantees zero well to well light cross talk greatly improving the accuracy and precision of photometric readings.

Internet will be increasingly used to view bioanalytical data

With an increasing number of contract research organisations available, purchasing managers or scientists are now confronted with a number of different options in terms of partnering a project with a particular CRO. Dr Andrew Penman reports.

Service wing can be key to the successful laboratory operation

Modern laboratories must be able to cope with diverse requirments and, as Stefan Holler reports, the service wing is key to their sucessful operation.

plastic consumables

Manufacture of precision plastic consumables by Treff is carried out by automated processes and is ISO 9001:2000 certified.

safe weighing environment

Weighing hazardous or potent substances within conventional fume cupboards is problematic.

The design of standard cabinets creates a roll in the airflow, which disrupts the operation of sensitive analytical balances.

How to protect research samples stored in -80°C deep freezers

In today's extensive fields of biological research and medical innovation, the market for -80°C deep freezers is increasing. Here we consider the latest developments in design.

Quantitative assay of tablets by transmission FT-NIR spectroscopy

In the pharmaceutical industry quality control is one of the most time-consuming activities in the production workflow. Kent T Møller, Magnus Tolleshaug and Thomas W. Jensen report on the use of near infrared spectroscopy for quality control analysis.

broad selectivity and high loading capacity of csps

Over the past 20 years the interest in developing more and more single enantiomeric drugs has grown tremendously since it has been demonstrated that the stereochemistry of such active substances is one of the major factors determining their bioactivity.

A new multipurpose research rheometer offers more flexibility

Most rheologists would prefer a rheometer that delivered state-of-the-art performance in both modes, since it would cut capital costs, and increase experimental flexibility with no performance loss. Such devices are now commercially available. George Dallas reports.

Parallel filtration ­ simple and efficient

Filtration is a very often used process in chemical synthesis. It is often a time consuming step and always linked to material loss.

Quick filtering using folded paper: the way to save time and money!

Björn Hobus outlines the advantages of carrying out filtration using pre-folded paper filters. Here he describes what to look for in a suitable filter paper.In almost every analytical laboratory ­ for example in quality assurance in the food industry or in environmental institutes ­ filtration processes are performed using paper filters.

Evaluating performance

Everyday more and more industries, be they manufacturing, process, utilities and service are required to conform to more and more rules and regulations:

For example the Climate Control Levy to promote efficient energy usage, to 21CFR part 11 for all companies working in the Pharmaceutical industries to promote consistent, repeatable and demonstrable levels of product production, to HTM2010/30 for clinical sterilisers and washer dryers operation, to ensure acceptable levels of hygiene.

Installing a steriliser ­ do not let it be just a pipedream?

Purchasing and owning a steriliser these days is nothing like it was say, 15 years ago. Times have changed. Regulations have moved on. The British have, at last, become Europeans! Christine Slade reports.

Guaranteeing the ionic purity of ultra-pure water

Scientists using sensitive techniques in analysis and bio-science need a supply of top-grade water containing less than 0.1µg/l of ionic impurities. How can they be sure that ionic purity of the water is good enough? Dr Paul Whitehead reports.

Single nucleotide polymorphisms tool analyses genetic variations

Debra Nickson looks at an error-free genotyping tool used to analyse genetic variation. Genotypes can be identified by simply looking for a colour change. Results are available instantaneously.

bioseparations use small volumes

Available from Bio-Nobile Oy, the PickPen transfer tool spearheads a new approach to magnetic particle separation.

In vitro cardiac electrophysiology and in vivo cardiovascular telemetry

The late detection of cardiotoxic side effects, such as electrocardiogram QT-interval prolongation, induced by compounds of pharmacological interest can dramatically impede drug research and development projects.

Frederic Sannajust reports.

Automated recording boosts drug screening capability for researchers

Dr Michael Fejtl reports on the automation of cDNA/mRNA injection and subsequent TEVC recording in Xenopus oocytes plated in 96-well micro-titer plates.

Rugged non-glass pH probes now available for any pH meter

Ijcke Schaepman reports on a a new series of non-glass pH probes which are virtually unbreakable. they also give faster, safer and more reliable measurements.

Avoid excess investment by making the most of existing hardware

Much of Europe's major investment in IT is being made by pharmaceutical and bioscience companies. While a new survey shows that this investment will continue to grow, some companies are turning to grid computing in a strategy that saves money and could prove good business for CROs too.

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