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To get to the tumor, which was buried deep in Brooke Zepp's abdomen and threatened to kill her within months, the organ transplant specialist said he first had to remove her stomach, pancreas, spleen, liver and small and large intestines.
The organs were chilled and preserved outside Zepp's body during a painstaking 15-hour operation at the University of Miami/Jackson Memorial Medical Center.
They were re-implanted in their normal position after the tumor -- which was about 2 inches (5 cm) in diameter and wrapped around Zepp's aorta and the base of two other arteries -- was removed.
Kato said that never before have six organs been removed from a patient's abdomen to allow doctors to go after a malignant growth previously considered inoperable because of its location.
"There's nothing really simple here," Kato, who trained as a surgeon at Osaka University in Japan, told Reuters on Monday. "I don't want to say acrobatic but it's kind of, in a way. It's a very tricky operation.
"We've done pieces of this surgery many times but not the whole thing like this," said the 11-year veteran of the University of Miami Transplant Institute who led a team of doctors that operated on Zepp.
Zepp was diagnosed with leiomyosarcoma, a rare form of cancer. But Kato said the type of surgery he performed on March 4 ultimately could benefit people with more common diseases.
"There might be a lot of applications," he said.
During the operation, Zepp, who was expected to be discharged from her Miami hospital this week, had many blood vessels replaced with artificial ones made of Gore-Tex.
"She came to me out of desperation,' Kato said. "I'm really glad it worked out well."