ITCM is a global manufacturer and leading innovator in customised machinery and systems for pharmaceutical packaging and processing.

 

The CycloGraph system is a centrifugally accelerated device for performing preparative chromatographic separations. The device spins a layer of adsorbent material coated as a flat ring on a glass backing. A solvent pump is used to apply the sample and mobile phase to the center of the spinning adsorbent ring. The centrifugal action accelerates the flow of the mobile phase through the adsorbent, separating the sample components as circular bands.

The mobile phase elutes continuously into a specially shaped collection channel inside the body of the instrument. Component bands are collected manually in test tubes or optionally by an automated fraction collector (not included). Separations occur quickly, usually within 20 minutes, versus the typical 90 to 120 minutes for preparative Thin Layer Chromatography (TLC) or Column Chromatography.